Perfil epidemiológico e anatomopatológico de pacientes diagnosticados com tumor estromal gastrointestinal

Abstract

Background - Gastrointestinal stromal tumors (GISTs) are specific mesenchymal tumors, covering most tumors previously considered smooth muscle tumors. They are believed to originated from instersticial cells of Cajal. Objective - To analyze the epidemiological and pathological profiles of patients diagnosed with GIST.Methods - The study included 59 patients who had pathological analysis of the tumor performed at the Pathology Service of Hospital São Vicente de Paulo, with a positive result for gastrointestinal stromal tumor. Results - GISTs usually occur in older adults, in our sample the mean age was 57 years. It may affect the entire gastrointestinal tract, but it is more frequent in the stomach, where we find it in 35.6% of patients. Histologically, The GISTs range from fusiform, epithelioid and mixed cell tumors, however, with fusiform predominance. In addition, most gastrointestinal stromal tumors express CD117 and CD34 protein. Conclusion - Men represent the majority, in the fifth decade of life, with gastrointestinal stromal tumor. The site most affected by the tumor was the stomach, which has a better prognosis compared to the small intestine. In addition, there was a predominance of fusiform cells and positive expression for CD117 and CD34 proteins.