Perfil sociodemográfico, medicamentoso e co-infeccioso em UTI por COVID-19

Abstract

The coronavirus pandemic declared on March 11, 2020, imposed a great challenge on the health system, faced with an emerging pathogen against which there was no readily available vaccine and which continues to surprise the scientific community due to its remarkable capacity for mutation and pathophysiological characteristics. Methodology: This quantitative observational research evaluated a patient profile characteristic of an initial pandemic context in a hospital west of Santa Catarina. Results: Concerning the patients assessed, there was a prevalence of males n=67 (61%) over females n=43 (39%). The age groups with the highest number of cases admitted to the ICU in the period evaluated were 50 to 59 years old n=37 (33.6%), from 60 to 69 years old n=19 (17.3%), and from 70 to 79 years old n=11 (10%), totaling 60.6%. The most common comorbidities observed among ICU patients were Systemic arterial hypertension (n=45, 27%), Obesity (n=22, 13%) and Diabetes mellitus (n=19, 11,3%). Bacterial infections prevailed among patients, and the most frequently observed microorganisms were Klebsiella pneumoniae (n=64, 34.41%) and Pseudomonas spp. (n=47, 25.27%), Candida albicans (n=29, 15.59%) and coagulase-negative Staphylococcus (n=14, 7.53%). The most prescribed antimicrobials were Meropenem (n=77, 21.63%), Tigecycline (n=55, 15.45%), Gentamicin (n=54, 15.17%), Ertapenem (n=28, 7, 87%) and Azithromycin (n=23, 6.46%). Regarding the clinical outcome of the patients evaluated, there was a prevalent rate of death (n=54, 49.1%) about discharges (n=46, 42.0%). The predominant age groups for death are between 50 and 79 years old, making up a total of 55.6% of patients. Conclusion: It is concluded that COVID-19 patients in the intensive care unit (ICU) have a profile of men over 50 years old, who have a previous comorbidity, and whose favorable outcome (hospital discharge) is inversely proportional to age.