Óleo essencial de Lavandula dentata (Lavanda): avaliação do rendimento, composição química e atividade anti-Staphylococcus aureus e Escherichia coli

Abstract

Bacterial resistance is a major concern in the 21st century, especially in veterinary medicine due to the inappropriate and indiscriminate use of antimicrobials, leading to a constant concern in One Health. The growing emergence of strains multiresistant to traditional antibiotics has increased studies related to the use of natural products with antimicrobial effects, highlighting the use of essential oils. In this study, the essential oil of Lavandula dentata (Lamiaceae) was used against strains of Staphylococcus aureus and Escherichia coli, two important pathogens in Veterinary Medicine. The work was carried out between June 2022 and December 2022, UFFS, Realeza Campus. Pruning was performed manually after 90 days and the oil was extracted using the steam distillation technique. Four strains of each microorganism were used, performing inoculum standardization and disk diffusion test to determine the susceptibility of the oil in relation to antimicrobials. The MICs of OEL ranged from 0.65 to 3.13% in standard strains of S. aureus and 2.08 to 3.13% in E. coli strains; the MBCs of OEL ranged from 3.13 to 25% in standard strains of S. aureus and 2.08 to 3.13% in E. coli strains, demonstrating that OEL has relevant antimicrobial activity against strains of S. aureus and E. coli. OEL presented 33 chemical components, with the major compounds being eucalyptol (36.18%), camphor (16.74%) and fenchone (15.79%).