Perfil epidemiológico, anatomopatológico, clínico e prognóstico de pacientes diagnosticados com adenocarcinoma de pâncreas

Abstract

ABSTRACT: Introduction: Pancreatic adenocarcinoma is one of the most belatedly diagnosed neoplasms, as a result, has a high mortality rate. Objective: Describe the profile of presentation and treatment of pancreatic cancer in the two largest hospitals in Passo Fundo, Rio Grande do Sul. Methods: this is a cross-sectional study, which analyzed 128 medical records of patients diagnosed with pancreatic cancer, confirmed by pathology, seen at the Hospital de Clínicas de Passo Fundo and Hospital São Vicente de Paulo, between January 2009 and December 2016. The findings were categorized according to epidemiology, clinical, anatomopathological presentation, treatment and survival. Results: Of the 128 patients, 51.5% were women, aged 65.2 ± 10.8 years. Pancreatic adenocarcinoma represented 94.5% of the total, in the head region (58.5%), locally advanced (34.3%) or metastatic (60.1%), associated with biliary obstruction in 55%. Pancreaticoduodenectoy was the curative technique of choice for 60.9% and 65.6% underwent palliative, surgical or clinical treatments. Conclusion: women represent the majority, in the seventh decade of life, with moderately differentiated pancreatic adenocarcinoma, located in the head of the pancreas. Locally advanced or metastatic disease was observed in most patients, with the treatment of choice being duodenopancreatectomy without pyloric preservation, in resectable tumors and opioid analgesia, associated with measures of support or alcoholization of the celiac plexus in the unresectable or terminal. The median survival was seven and a half months, with more than 92% progressing to deat.