Toxicidade, tromboembolismo venoso, capacidade funcional e o impacto financeiro entre pacientes oncológicos em terapia sistêmica

Abstract

Introduction: Currently, there are three main forms of therapy to treat cancer: surgery, radiotherapy, which is divided into teletherapy and brachytherapy, and finally chemotherapy, characterized by the systemic infusion of drugs. This last therapeutic modality is commonly associated with various uncomfortable clinical complications arising from treatment-related toxicity. These manifestations negatively affect the patient's quality of life and functionality, as well as increasing the risk of even more severe complications. Objective: To analyze the presence of an association between the risk of general toxicity, risk of venous thromboembolism toxicity, functional capacity and financial impact among cancer patients undergoing systemic therapy. Method: This is a cross-sectional quantitative study carried out in the oncology department of a regional hospital located in western Santa Catarina. Data was collected through interviews and checking electronic medical records, using a sociodemographic and clinical questionnaire and four clinical assessment scales. The data collected was subjected to statistical analysis using the Statistical Package for the Social Sciences (SPSS) system, with parametric and non-parametric tests. Results: At the end of the analysis, the main results were the presence of a correlation between clinical and sociodemographic variables with toxicities and functional capacity. Conclusion: It can be concluded that systemic antineoplastic treatment, associated with other sociodemographic factors, influences a greater risk of toxicities and a decrease in functional capacity.