O papel dos testes moleculares na estratificação de risco de malignidade em nódulos tireoideanos

Abstract

This study aimed to evaluate the role of molecular testing in risk stratification of indeterminate thyroid nodules, considering their usefulness in distinguishing benign from malignant lesions. The relevance of the topic lies in the clinical impact of avoiding invasive procedures without compromising patient safety. The literature review demonstrated that molecular tests complement clinical, cytological, and ultrasonographic assessment, increasing diagnostic accuracy and supporting more individualized therapeutic decisions. It is concluded that these tests play an important role in managing indeterminate nodules by helping reduce unnecessary surgeries and guiding more appropriate and patient-centered care strategies.