Efeito da suplementação de vitamina C em pacientes com Diabetes Mellitus tipo 2: uma revisão sistemática

Abstract

Type 2 diabetes mellitus consists of an array of dysfunctions characterized by hyperglycemia and resulting from the combination of resistance to insulin action, inadequate insulin secretion, and excessive or inappropriate glucagon secretion, which can be caused by increased weight and obesity. Diabetic patients may have an increase in oxidation in different parts of the body and structures, to avoid it, the recommendation is a ingestion of sources of vitamin C, since it is not produced by the body. The aim of this study was to investigate the relationship between vitamin C supplementation, also known as ascorbic acid administered in patients with type 2 diabetes. To complete the following study, the literature review methodology was applied and pieces from different selected sources of works were used to compose the present text. In these analyzes, data related to the target public, dosage, time, positive and limiting aspects of each research were observed. As a result of the experiments there are weights of administration of vitamin C, presenting effects as antioxidants and markers of lipid peroxidation; reducing blood glucose and improving glycosylated hemoglobin; effect on oxidative stress of skeletal muscle and insulin sensitivity; inflammation and metabolic markers in obese hypertensive adults and in the reduction of blood pressure and arterial stiffness. It was concluded that it is possible to treat type 2 diabetic patients with vitamin C supplementation and that associated with a healthy diet will bring different positive aspects to the subjects' quality of life.